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ICOSLG Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ICOSLG in WB. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Meerschweinchen, Pferd und Schwein.
Produktnummer ABIN2789696

Kurzübersicht für ICOSLG Antikörper (N-Term) (ABIN2789696)

Target

Alle ICOSLG Antikörper anzeigen
ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reaktivität

Human, Rind (Kuh), Meerschweinchen, Pferd, Schwein

Wirt

  • 51
  • 46
  • 8
  • 1
Kaninchen

Klonalität

  • 65
  • 40
  • 1
Polyklonal

Konjugat

  • 62
  • 10
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ICOSLG Antikörper ist unkonjugiert

Applikation

  • 47
  • 41
  • 41
  • 35
  • 20
  • 16
  • 9
  • 8
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 24
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    VDSRYRNRAL MSPAGMLRGD FSLRLFNVTP QDEQKFHCLV LSQSLGFQEV

    Homologie

    Cow: 92%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Pig: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ICOSLG. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human ICOSLG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 302 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

    Andere Bezeichnung

    ICOSLG

    Hintergrund

    ICOSLG is a ligand for the T-cell-specific cell surface receptor ICOS. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. ICOSLG could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
    Alias Symbols: B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS
    Protein Interaction Partner: ICOS,
    Protein Size: 302

    Molekulargewicht

    33 kDa

    Gen-ID

    23308

    NCBI Accession

    NM_015259, NP_056074

    UniProt

    O75144

    Pathways

    Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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