ICOSLG Antikörper (N-Term)
Kurzübersicht für ICOSLG Antikörper (N-Term) (ABIN2789696)
Target
Alle ICOSLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- VDSRYRNRAL MSPAGMLRGD FSLRLFNVTP QDEQKFHCLV LSQSLGFQEV
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Homologie
- Cow: 92%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Pig: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ICOSLG. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ICOSLG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 302 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
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Andere Bezeichnung
- ICOSLG
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Hintergrund
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ICOSLG is a ligand for the T-cell-specific cell surface receptor ICOS. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. ICOSLG could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Alias Symbols: B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS
Protein Interaction Partner: ICOS,
Protein Size: 302 -
Molekulargewicht
- 33 kDa
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Gen-ID
- 23308
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NCBI Accession
- NM_015259, NP_056074
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UniProt
- O75144
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Pathways
- Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Target
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