Integrin Alpha2b Antikörper (N-Term)

Produktnummer ABIN2789680

Der Kaninchen Polyklonal anti-Integrin Alpha2b Antikörper (ABIN2789680) detektiert spezifisch Integrin Alpha2b in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Schwein, Saccharomyces cerevisiae und Pferd.

Kurzübersicht für Integrin Alpha2b Antikörper (N-Term) (ABIN2789680)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Kaninchen, Schwein, Saccharomyces cerevisiae, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Integrin Alpha2b Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ITGA2B Antibody - N-terminal region

Sequenz: QGLGASVVSW SDVIVACAPW QHWNVLEKTE EAEKTPVGSC FLAQPESGRR

Homologie: Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ITGA2B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63955-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: ITGA2B

Hintergrund:

Background Information: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Gene Name: Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Alternative Symbols: GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2, BDPLT16, PPP1R93

Protein Name: Integrin alpha-IIb

Molekulargewicht: 16kDa

Gen-ID: 3674

NCBI Accession: NP_000410

UniProt: P08514

Pathways: Integrin Complex