Integrin Alpha2b Antikörper (N-Term)

Produktnummer ABIN2789680

Dieses Anti-Integrin Alpha2b-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Integrin Alpha2b in WB. Geeignet für Human, Maus, Ratte, Hund, Meerschweinchen, Schwein, Kaninchen, Saccharomyces cerevisiae und Pferd.

Kurzübersicht für Integrin Alpha2b Antikörper (N-Term) (ABIN2789680)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Schwein, Kaninchen, Saccharomyces cerevisiae, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Integrin Alpha2b Antikörper

Bindungsspezifität: N-Term

Sequenz: QGLGASVVSW SDVIVACAPW QHWNVLEKTE EAEKTPVGSC FLAQPESGRR

Homologie: Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ITGA2B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1039 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: ITGA2B

Hintergrund: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Alias Symbols: CD41, CD41B, GP2B, GPIIb, GTA, HPA3, GT, BDPLT2
Protein Interaction Partner: FBXO6, PRKACA, CAMK2A, ITGA2B, AUP1, CIB1, CLNS1A, VWF, TLN1, F2, CD36, ITGB3, FGA, COL1A2, COL2A1, CALR, GRB2, RNF181,
Protein Size: 1039

Molekulargewicht: 16 kDa

Gen-ID: 3674

NCBI Accession: NM_000419, NP_000410

UniProt: P08514

Pathways: Integrin Complex