Exonuclease 1 Antikörper (N-Term)
Kurzübersicht für Exonuclease 1 Antikörper (N-Term) (ABIN2789520)
Target
Alle Exonuclease 1 (EXO1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- ILVFDGCTLP SKKEVERSRR ERRQANLLKG KQLLREGKVS EARECFTRSI
-
Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 86%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against EXO1. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 803 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Exonuclease 1 (EXO1)
-
Andere Bezeichnung
- EXO1
-
Hintergrund
-
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Alias Symbols: HEX1, hExoI
Protein Interaction Partner: YWHAB, MLH1, PCNA, UBC, SUMO2, YWHAQ, YWHAZ, YWHAH, YWHAG, YWHAE, MSH2, KPNA4, KPNB1, SFN, ATM, PMS2, PMS1, BLM, MSH3,
Protein Size: 803 -
Molekulargewicht
- 89 kDa
-
Gen-ID
- 9156
-
NCBI Accession
- NM_003686, NP_003677
-
UniProt
- Q9UQ84
-
Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
-