IL13 Receptor alpha 1 Antikörper (N-Term)

Produktnummer ABIN2789491

Der Kaninchen Polyklonal Anti-IL13 Receptor alpha 1-Antikörper wurde für WB validiert. Er ist geeignet, IL13 Receptor alpha 1 in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein und Schaf zu detektieren.

Kurzübersicht für IL13 Receptor alpha 1 Antikörper (N-Term) (ABIN2789491)

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL13 Receptor alpha 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL13 Receptor alpha 1 Antikörper

Bindungsspezifität: N-Term

Sequenz: VSVENLCTVI WTWNPPEGAS SNCSLWYFSH FGDKQDKKIA PETRRSIEVP

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 100%, Rat: 86%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against IL13RA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of IL13RA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 427 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL13 Receptor alpha 1

Target: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Andere Bezeichnung: IL13RA1

Hintergrund: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Alias Symbols: CD213A1, IL-13Ra, NR4
Protein Interaction Partner: UBC, IL2RG, TMEM39B, ELAVL1, TRAF3IP1, DLG4, TYK2, IL4R, IL13,
Protein Size: 427

Molekulargewicht: 47 kDa

Gen-ID: 3597

NCBI Accession: NM_001560, NP_001551

UniProt: P78552

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response