Cyclin B2 Antikörper (N-Term)
Kurzübersicht für Cyclin B2 Antikörper (N-Term) (ABIN2789489)
Target
Alle Cyclin B2 (CCNB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- IGNRVTTRAA QVAKKAQNTK VPVQPTKTTN VNKQLKPTAS VKPVQMEKLA
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Homologie
- Cow: 83%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 83%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CCNB2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 398 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cyclin B2 (CCNB2)
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Andere Bezeichnung
- CCNB2
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Hintergrund
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Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Alias Symbols: HsT17299
Protein Interaction Partner: CKS2, CKS1B, CDK1, CDK2, MCM2, CDKN1A, ATR, UBC, tat, TSPYL2, TGFBR2,
Protein Size: 398 -
Molekulargewicht
- 45 kDa
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Gen-ID
- 9133
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NCBI Accession
- NM_004701, NP_004692
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UniProt
- O95067
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Pathways
- Zellzyklus, M Phase
Target
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