PINK1 Antikörper (N-Term)
Kurzübersicht für PINK1 Antikörper (N-Term) (ABIN2789443)
Target
Alle PINK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- GCAGPCGRAV FLAFGLGLGL IEEKQAESRR AVSACQEIQA IFTQKSKPGP
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Homologie
- Cow: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PINK1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 581 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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Andere Bezeichnung
- PINK1
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Hintergrund
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This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
Alias Symbols: BRPK, FLJ27236, PARK6
Protein Interaction Partner: IMMT, RHOT2, MCL1, BCL2L2, BCL2L1, UBC, BAG2, CRLS1, FBXO7, SARM1, RB1CC1, TOMM20, VIM, TRAF6, HSPA1B, HSPA1A, PARK2, HSP90AA1, TOLLIP, MAP3K7, IRAK1, RICTOR, SENP8, MAPKAP1, COPS8, UBE2M, AKT1, NEDD8, PINK1, TOMM22, RHOT1, HTRA2, PARK7, CDC37, TOMM40, TO
Protein Size: 581 -
Molekulargewicht
- 63 kDa
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Gen-ID
- 65018
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NCBI Accession
- NM_032409, NP_115785
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UniProt
- Q9BXM7
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Pathways
- Autophagie
Target
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