TPMT Antikörper (C-Term)

Produktnummer ABIN2789428

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TPMT in WB. Es zeigt Reaktivität gegenüber Proben von Human, Hund und Schwein.

Kurzübersicht für TPMT Antikörper (C-Term) (ABIN2789428)

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Reaktivität: Human, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TPMT Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TPMT Antibody - C-terminal region

Sequenz: RGALVAINPG DRKCYADTMF SLLGKKFQYL LCVLSYDPTK HPGPPFYVPH

Homologie: Dog: 79%, Human: 100%, Pig: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TPMT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63262-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TPMT

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Andere Bezeichnung: TPMT

Hintergrund:

Background Information: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Gene Name: Thiopurine S-methyltransferase

Alternative Symbols: TPMTD

Protein Name: Thiopurine S-methyltransferase

Molekulargewicht: 27kDa

Gen-ID: 7172

NCBI Accession: NP_000358

UniProt: P51580