TPMT Antikörper (C-Term)
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- Target Alle TPMT Antikörper anzeigen
- TPMT (Thiopurine S-Methyltransferase (TPMT))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Hund, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TPMT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RGALVAINPG DRKCYADTMF SLLGKKFQYL LCVLSYDPTK HPGPPFYVPH
- Homologie
- Dog: 79%, Human: 100%, Pig: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TPMT. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product TPMT Primärantikörper
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anti-Thiopurine S-Methyltransferase (TPMT) (AA 26-227) antibody
TPMT Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) (AA 1-245) antibodyTPMT Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1B5 unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) antibodyTPMT Reaktivität: Human, Hund WB, IHC, IHC (p), FACS Wirt: Maus Monoclonal 4C1 unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) (AA 4-244) antibodyTPMT Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) (AA 1-245) antibodyTPMT Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) (N-Term) antibodyTPMT Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) antibodyTPMT Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) antibodyTPMT Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) antibodyTPMT Reaktivität: Human, Maus IF Wirt: Kaninchen Polyclonal unconjugated
anti-Thiopurine S-Methyltransferase (TPMT) antibodyTPMT Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 245 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TPMT (Thiopurine S-Methyltransferase (TPMT))
- Andere Bezeichnung
- TPMT (TPMT Produkte)
- Hintergrund
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This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Alias Symbols: -
Protein Interaction Partner: APP, UBC,
Protein Size: 245 - Molekulargewicht
- 27 kDa
- Gen-ID
- 7172
- NCBI Accession
- NM_000367, NP_000358
- UniProt
- P51580
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