SCARB1 Antikörper (N-Term)

Produktnummer ABIN2789394

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-SCARB1 Antikörper (ABIN2789394) detektiert spezifisch SCARB1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für SCARB1 Antikörper (N-Term) (ABIN2789394)

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCARB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SCARB1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SCARB1 Antibody - N-terminal region

Sequenz: LEYRTFQFQP SKSHGSESDY IVMPNILVLG AAVMMENKPM TLKLIMTLAF

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SCARB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63158-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SCARB1 Antikörper (ABIN2789394)

Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

Details zu SCARB1

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Andere Bezeichnung: SCARB1

Hintergrund:

Background Information: The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Scavenger receptor class B, member 1

Alternative Symbols: CLA1, SRB1, CLA-1, SR-BI, CD36L1, HDLQTL6

Protein Name: Scavenger receptor class B member 1 Ensembl ENSP00000343795

Molekulargewicht: 56kDa

Gen-ID: 949

NCBI Accession: NP_001076428

UniProt: F8W8N0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interaktom