SCARB1 Antikörper (N-Term)

Produktnummer ABIN2789394

Dieses Anti-SCARB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SCARB1 in WB und IHC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen und Kaninchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für SCARB1 Antikörper (N-Term) (ABIN2789394)

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCARB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SCARB1 Antikörper

Bindungsspezifität: N-Term

Sequenz: LEYRTFQFQP SKSHGSESDY IVMPNILVLG AAVMMENKPM TLKLIMTLAF

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SCARB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 506 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SCARB1 Antikörper (ABIN2789394)

Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

Details zu SCARB1

Target: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Andere Bezeichnung: SCARB1

Hintergrund: The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD36L1, CLA-1, CLA1, MGC138242, SR-BI, SRB1, HDLQTL6
Protein Interaction Partner: KRTAP10-9, KRTAP5-9, UBC, FBXO6, CAND1, CUL1, APOA2, APOA1, PDZK1, PEX5, APOE,
Protein Size: 506

Molekulargewicht: 56 kDa

Gen-ID: 949

NCBI Accession: NM_001082959, NP_001076428

UniProt: F8W8N0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interaktom