MCC Antikörper (C-Term)

Produktnummer ABIN2789347

Produktdetails anti-MCC Antikörper

Target: MCC (Mutated in Colorectal Cancers (MCC))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SSTSSGSKDK PGKECADAAS PALSLAELRT TCSENELAAE FTNAIRREKK

Homologie: Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MCC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 829 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MCC

Target: MCC (Mutated in Colorectal Cancers (MCC))

Andere Bezeichnung: MCC (MCC Produkte)

Hintergrund: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp762O1615, FLJ38893, FLJ46755, MCC1
Protein Interaction Partner: CSNK1E, ERBB2IP, CBX5, GTF2E2, APP, DYNC1I1, NEK2, NFKBIB, STRIP1, VPS35, STRN3, STRN4, SNRNP200, PDCD10, PAICS, PSME3, CCNA1, EIF3A, STK24, EZR, VHL, VDAC1, VCP, TPM3, TARS, STRN, PSMD2, PPP2R1A, PFKP, PFAS, MYH10, MTHFD1, MARS, LTA4H, KRT18, IARS, HPRT1
Protein Size: 829

Molekulargewicht: 91 kDa

Gen-ID: 4163

NCBI Accession: NM_002387, NP_002378