Poliovirus Receptor Antikörper (N-Term)

Produktnummer ABIN2789343

Der Kaninchen Polyklonal anti-Poliovirus Receptor Antikörper (ABIN2789343) detektiert spezifisch Poliovirus Receptor in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Poliovirus Receptor Antikörper (N-Term) (ABIN2789343)

Target: Poliovirus Receptor (PVR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Poliovirus Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Poliovirus Receptor Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PVR Antibody - N-terminal region

Sequenz: FHQTQGPSYS ESKRLEFVAA RLGAELRNAS LRMFGLRVED EGNYTCLFVT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PVR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63030-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: PVR

Hintergrund:

Background Information: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Poliovirus receptor

Alternative Symbols: PVS, HVED, CD155, NECL5, TAGE4, Necl-5

Protein Name: Poliovirus receptor

Molekulargewicht: 45kDa

Gen-ID: 5817

NCBI Accession: NP_006496

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom