Poliovirus Receptor Antikörper (N-Term)

Produktnummer ABIN2789343

Dieses Anti-Poliovirus Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Poliovirus Receptor in WB und IHC. Geeignet für Human.

Kurzübersicht für Poliovirus Receptor Antikörper (N-Term) (ABIN2789343)

Target: Poliovirus Receptor (PVR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Poliovirus Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Poliovirus Receptor Antikörper

Bindungsspezifität: N-Term

Sequenz: FHQTQGPSYS ESKRLEFVAA RLGAELRNAS LRMFGLRVED EGNYTCLFVT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PVR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 417 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: PVR

Hintergrund: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, SLC30A2, TIGIT, TNFRSF12A, WNK1, PLA2G3, UBC, ZC3HAV1, ELAVL1, CD226, PVRL3, PVRL1, CD96, AP1M2, DYNLT3, VTN, PVR, DYNLT1,
Protein Size: 417

Molekulargewicht: 45 kDa

Gen-ID: 5817

NCBI Accession: NM_006505, NP_006496

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom