DCTN3 Antikörper (C-Term)

Produktnummer ABIN2789148

Produktdetails anti-DCTN3 Antikörper

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCTN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ARLQRLAQIH IQQQDQCVEI TEESKALLEE YNKTTMLLSK QFVQWDELLC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DCTN3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 186 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DCTN3

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Andere Bezeichnung: DCTN3 (Dctn3 Produkte)

Hintergrund: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DCTN-22, DCTN22, MGC111190
Protein Interaction Partner: LMNB1, FLNB, FHL2, LEO1, TNKS1BP1, NUP85, CCAR2, ACTR10, DCTN2, ACTR1A, UBC, ACTR1B, DYNLT3, ATXN1, GSK3B, Dctn3, Dctn1, Capza1, PBX2,
Protein Size: 186

Molekulargewicht: 20 kDa

Gen-ID: 11258

NCBI Accession: NM_001248, NP_001239

UniProt: O75355

Pathways: M Phase