DCTN3 Antikörper (C-Term)

Produktnummer ABIN2789148

Der Kaninchen Polyklonal Anti-DCTN3-Antikörper wurde für WB validiert. Er ist geeignet, DCTN3 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für DCTN3 Antikörper (C-Term) (ABIN2789148)

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCTN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DCTN3 Antikörper

Bindungsspezifität: C-Term

Sequenz: ARLQRLAQIH IQQQDQCVEI TEESKALLEE YNKTTMLLSK QFVQWDELLC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DCTN3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 186 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DCTN3

Target: DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))

Andere Bezeichnung: DCTN3

Hintergrund: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DCTN-22, DCTN22, MGC111190
Protein Interaction Partner: LMNB1, FLNB, FHL2, LEO1, TNKS1BP1, NUP85, CCAR2, ACTR10, DCTN2, ACTR1A, UBC, ACTR1B, DYNLT3, ATXN1, GSK3B, Dctn3, Dctn1, Capza1, PBX2,
Protein Size: 186

Molekulargewicht: 20 kDa

Gen-ID: 11258

NCBI Accession: NM_001248, NP_001239

UniProt: O75355

Pathways: M Phase