CTPS2 Antikörper (N-Term)

Produktnummer ABIN2789147

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CTPS2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Schwein, Kaninchen, Zebrafisch (Danio rerio) und Meerschweinchen.

Kurzübersicht für CTPS2 Antikörper (N-Term) (ABIN2789147)

Target: CTPS2 (CTP Synthase II (CTPS2))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Schwein, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CTPS2 Antikörper

Bindungsspezifität: N-Term

Sequenz: AKRENFCNIH VSLVPQLSAT GEQKTKPTQN SVRALRGLGL SPDLIVCRSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CTPS2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 586 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CTPS2

Target: CTPS2 (CTP Synthase II (CTPS2))

Andere Bezeichnung: CTPS2

Hintergrund: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Alias Symbols: DKFZp686C17207, FLJ43358, MGC32997
Protein Interaction Partner: CTPS2, SPG21, RNF2, LRSAM1, EHD4, EHD1, PLIN3, MTMR2, WARS, PRKDC, NUCB1, METTL1, KTN1, HSF1, GTF2I, DHPS, RPL37A, RPL23A, FGFR1, CTBP2, UBC, SUMO2, OTUD5,
Protein Size: 586

Molekulargewicht: 64 kDa

Gen-ID: 56474

NCBI Accession: NM_175859, NP_787055

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process