KIF7 Antikörper (C-Term)

Produktnummer ABIN2788987

Produktdetails anti-KIF7 Antikörper

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RDLVHAPLPL TWKRSSLCGE EQGSPEELRQ REAAEPLVGR VLPVGEAGLP

Homologie: Cow: 92%, Dog: 79%, Human: 100%, Mouse: 77%, Pig: 100%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against KIF7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human KIF7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Andere Bezeichnung: KIF7 (KIF7 Produkte)

Hintergrund: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Alias Symbols: ACLS, AGBK, HLS2, JBTS12, UNQ340
Protein Size: 829

Molekulargewicht: 91 kDa

Gen-ID: 374654

NCBI Accession: NM_198525, NP_940927

UniProt: Q2M1P5

Pathways: Hedgehog Signalweg