F11R Antikörper (C-Term)

Produktnummer ABIN2788778

Der Kaninchen Polyklonal anti-F11R Antikörper wird verwendet zum Nachweis von F11R in Proben von Human, Rind (Kuh), Hund, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für F11R Antikörper (C-Term) (ABIN2788778)

Target: F11R (F11 Receptor (F11R))

Reaktivität: Human, Rind (Kuh), Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F11R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-F11R Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: F11R Antibody - C-terminal region

Sequenz: AVLVTLILLG ILVFGIWFAY SRGHFDRTKK GTSSKKVIYS QPSARSEGEF

Homologie: Cow: 85%, Dog: 92%, Human: 100%, Pig: 92%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against F11R. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61361-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: F11R

Hintergrund:

Background Information: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Gene Name: F11 receptor

Alternative Symbols: JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1

Protein Name: Junctional adhesion molecule A

Molekulargewicht: 33kDa

Gen-ID: 50848

NCBI Accession: NP_058642

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization