F11R Antikörper (C-Term)

Produktnummer ABIN2788778

Produktdetails anti-F11R Antikörper

Target: F11R (F11 Receptor (F11R))

Bindungsspezifität: C-Term

Reaktivität: Human, Rind (Kuh), Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F11R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AVLVTLILLG ILVFGIWFAY SRGHFDRTKK GTSSKKVIYS QPSARSEGEF

Homologie: Cow: 85%, Dog: 92%, Human: 100%, Pig: 92%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against F11R. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 299 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: F11R (F11R Produkte)

Synonyme: CD321 antikoerper, JAM antikoerper, JAM1 antikoerper, JAMA antikoerper, JCAM antikoerper, KAT antikoerper, PAM-1 antikoerper, 9130004G24 antikoerper, AA638916 antikoerper, ESTM33 antikoerper, JAM-1 antikoerper, JAM-A antikoerper, Jcam antikoerper, Jcam1 antikoerper, Ly106 antikoerper, Jam1 antikoerper, F11 receptor antikoerper, F11R antikoerper, F11r antikoerper

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Alias Symbols: CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Protein Interaction Partner: SGTA, PEX19, BDNF, ELAVL1, UBC, PICK1, F11R, CGN, MPDZ, PARD3, F2RL2, TJP1, ASIP, CASK, PRKCA, PTPRB, MLLT4, ITGAL, CSNK2A1,
Protein Size: 299

Molekulargewicht: 33 kDa

Gen-ID: 50848

NCBI Accession: NM_016946, NP_058642

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization