RCC1 Antikörper (C-Term)

Produktnummer ABIN2788760

Dieser Anti-RCC1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von RCC1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für RCC1 Antikörper (C-Term) (ABIN2788760)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RCC1 Antikörper

Bindungsspezifität: C-Term

Sequenz: AWGMGTNYQL GTGQDEDAWS PVEMMGKQLE NRVVLSVSSG GQHTVLLVKD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RCC1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 421 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Andere Bezeichnung: RCC1

Hintergrund: RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Alias Symbols: CHC1, RCC1-I, SNHG3-RCC1
Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, MDM2, SUZ12, RNF2, PTMA, HDAC9, HMGA1, VCAM1, ITGA4, FN1, U2AF1, RANBP1, RAN, HNRNPM, HNRNPK, LUC7L3, SF3B6, NCSTN, ACIN1, RBM14, HDGF, SPRED1, FLAD1, WIZ, LRIF1, CSAD, SDF4, TRMT2A, DDAH2, FAF1, NUDT21, CCT7, TUBB3, CDK2AP2, KMT
Protein Size: 421

Molekulargewicht: 45 kDa

Gen-ID: 1104

NCBI Accession: NM_001269, NP_001260

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus