IRAK2 Antikörper (C-Term)

Produktnummer ABIN2788725

Produktdetails anti-IRAK2 Antikörper

Target: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSSEACVGLE PPQDVTETSW QIEINEAKRK LMENILLYKE EKVDSIELFG

Homologie: Cow: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Yeast: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against IRAK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IRAK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 625 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IRAK2

Target: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Andere Bezeichnung: IRAK2 (IRAK2 Produkte)

Synonyme: IRAK-2 antikoerper, 6330415L08Rik antikoerper, AI649099 antikoerper, interleukin 1 receptor associated kinase 2 antikoerper, interleukin-1 receptor-associated kinase 2 antikoerper, IRAK2 antikoerper, Irak2 antikoerper

Hintergrund: IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
Alias Symbols: IRAK-2, MGC150550
Protein Interaction Partner: TNFSF9, TRAF6, HSP90AA1, PSEN1, IRAK1, IL1R1, MYD88, UBC, TIRAP, SESTD1, ZC3H12C, ZC3H12A, FASTKD5, ADCK3, YTHDF1, TOLLIP, IRAK4, TARDBP, SARM1, SNRNP200, IRAK3, CDC37, IQSEC1, IQCB1, BAG3, STT3A, ARAF, TNFAIP3, MME, TICAM2, SMURF1, IRAK2, TLR4, SMAD2, HR
Protein Size: 625

Molekulargewicht: 69 kDa

Gen-ID: 3656

NCBI Accession: NM_001570, NP_001561

UniProt: O43187

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades