XPA Antikörper (C-Term)

Produktnummer ABIN2788719

Der Kaninchen Polyklonal Anti-XPA-Antikörper wurde für WB validiert. Er ist geeignet, XPA in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Meerschweinchen und Pferd zu detektieren.

Kurzübersicht für XPA Antikörper (C-Term) (ABIN2788719)

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-XPA Antikörper

Bindungsspezifität: C-Term

Sequenz: MKQKKFDKKV KELRRAVRSS VWKRETIVHQ HEYGPEENLE DDMYRKTCTM

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against XPA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 273 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Andere Bezeichnung: XPA

Hintergrund: This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: XP1, XPAC
Protein Interaction Partner: NDEL1, TRIM27, HERC2, ATR, PRKDC, ATM, HMGB1, ERCC1, DDB2, DDB1, RPA1, XPC, POLR2A, HHV8GK18_gp81, GTF2H1, ERCC6, RPA2, MSH3, MSH2, XAB2, GPN1, RPA4, RASSF1, GTF2E2, EP300,
Protein Size: 273

Molekulargewicht: 31 kDa

Gen-ID: 7507

NCBI Accession: NM_000380, NP_000371

UniProt: P23025

Pathways: DNA Reparatur