CD44 Antikörper (C-Term)

Produktnummer ABIN2788656

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD44 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd und Meerschweinchen.

Kurzübersicht für CD44 Antikörper (C-Term) (ABIN2788656)

Target: CD44

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD44 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD44 Antikörper

Bindungsspezifität: C-Term

Sequenz: SGNGAVEDRK PSGLNGEASK SQEMVHLVNK ESSETPDQFM TADETRNLQN

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CD44. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CD44

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 361 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.
Alias Symbols: CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1, HUTCH-I
Protein Interaction Partner: UBC, NF2, NEDD8, BAG1, DPP8, VHL, SRC, ANK1, ATF2, FMNL1, IQGAP1, SLC3A2, STAT3, ITGB1, FLOT2, EP300, CAV1, PRKCZ, ELAVL1, ARHGEF12, ARHGEF1, PKN1, DMP1, HMMR, TIAM1, ERBB4, VAV2, GARS, TGFBR2, TGFBR1, CD4, MMP7, SRGN, SPP1, LCK, IGFBP3, CD74, FYN, FGF2,
Protein Size: 361

Molekulargewicht: 40 kDa

Gen-ID: 960

NCBI Accession: NM_001001391, NP_001001391

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling