VEGFA Antikörper (C-Term)

Produktnummer ABIN2788641

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VEGFA in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Pferd, Schaf und Meerschweinchen.

Kurzübersicht für VEGFA Antikörper (C-Term) (ABIN2788641)

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Pferd, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEGFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-VEGFA Antikörper

Bindungsspezifität: C-Term

Sequenz: SFLQHNKCEC RPKKDRARQE KKSVRGKGKG QKRKRKKSRY KSWSVCDKPR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against VEGFA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 351 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu VEGFA

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Andere Bezeichnung: VEGFA

Hintergrund: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome.
Alias Symbols: MGC70609, MVCD1, VEGF, VPF
Protein Interaction Partner: ILF3, HNRNPL, NRP1, FLT1, LYVE1, KDR, PRRG4, VPS35, U2AF1, Flt4, ELAVL1, CRYAB, HNRNPD, HGS, UBC, HSP90AA1, HSPA4, YBX3, ADAMTS1, IGFBP7, NRP2, VEGFB, SEMA3F, PGF, EPHB2, TNXB, GPC1, VTN, VEGFA, SPARC, AKT1, YBX1, CTGF, RB1, HIF1A,
Protein Size: 351

Molekulargewicht: 40 kDa

Gen-ID: 7422

NCBI Accession: NM_001204385, NP_001191314

UniProt: P15692

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling