GFM1 Antikörper (C-Term)

Produktnummer ABIN2788619

Der Kaninchen Polyklonal anti-GFM1 Antikörper wird verwendet zum Nachweis von GFM1 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd und Schwein. Er wurde validiert für WB.

Kurzübersicht für GFM1 Antikörper (C-Term) (ABIN2788619)

Target: GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GFM1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Gfm1 Antibody - C-terminal region

Sequenz: ELRSCTEGKG EYTMEYCRYQ PCSPSTQEEL INKYLEATGQ LPVKKGKAKN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Gfm1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60908-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GFM1

Target: GFM1 (G-Elongation Factor, Mitochondrial 1 (GFM1))

Andere Bezeichnung: Gfm1

Hintergrund:

Background Information: Gfm1 is a mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Gfm1 catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Gfm1 does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.

Gene Name: G elongation factor, mitochondrial 1

Alternative Symbols: Gfm, AW545374, D3Wsu133, D3Wsu133e

Protein Name: Elongation factor G, mitochondrial

Molekulargewicht: 83kDa

Gen-ID: 28030

NCBI Accession: NP_613057

UniProt: Q8K0D5