MAPKSP1 Antikörper (N-Term)

Produktnummer ABIN2788404

Produktdetails anti-MAPKSP1 Antikörper

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKSP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LPSVEGLHAI VVSDRDGVPV IKVANDNAPE HALRPGFLST FALATDQGSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LAMTOR3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LAMTOR3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPKSP1

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Andere Bezeichnung: LAMTOR3 (MAPKSP1 Produkte)

Hintergrund: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
Alias Symbols: MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3
Protein Interaction Partner: NIF3L1, LAMTOR2, IBTK, MBD2, BHMT, PEF1, C19orf70, MRPL43, PRR3, LPCAT1, MRPS9, MRPS35, MRPL47, TOMM22, DDX28, TSR1, RNMTL1, LAMTOR1, NDUFB11, TMCO1, MRPL39, PTRH2, RAB14, MRPL51, MRPL22, UQCRQ, PUF60, RAB31, TOMM40, MSLN, TOMM70A, NUPL1, SPCS2, PICALM, V
Protein Size: 124

Molekulargewicht: 13 kDa

Gen-ID: 8649

NCBI Accession: NM_021970, NP_068805

UniProt: Q9UHA4

Pathways: PI3K-Akt Signalweg