MAPKSP1 Antikörper (N-Term)

Produktnummer ABIN2788404

Dieser Anti-MAPKSP1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MAPKSP1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für MAPKSP1 Antikörper (N-Term) (ABIN2788404)

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKSP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAPKSP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: LPSVEGLHAI VVSDRDGVPV IKVANDNAPE HALRPGFLST FALATDQGSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LAMTOR3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LAMTOR3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPKSP1

Target: MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))

Andere Bezeichnung: LAMTOR3

Hintergrund: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
Alias Symbols: MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3
Protein Interaction Partner: NIF3L1, LAMTOR2, IBTK, MBD2, BHMT, PEF1, C19orf70, MRPL43, PRR3, LPCAT1, MRPS9, MRPS35, MRPL47, TOMM22, DDX28, TSR1, RNMTL1, LAMTOR1, NDUFB11, TMCO1, MRPL39, PTRH2, RAB14, MRPL51, MRPL22, UQCRQ, PUF60, RAB31, TOMM40, MSLN, TOMM70A, NUPL1, SPCS2, PICALM, V
Protein Size: 124

Molekulargewicht: 13 kDa

Gen-ID: 8649

NCBI Accession: NM_021970, NP_068805

UniProt: Q9UHA4

Pathways: PI3K-Akt Signalweg