MAPKAP Kinase 3 Antikörper (C-Term)

Produktnummer ABIN2788402

Produktdetails anti-MAPKAP Kinase 3 Antikörper

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKAP Kinase 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KEEMTSALAT MRVDYDQVKI KDLKTSNNRL LNKRRKKQAG SSSASQGCNN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAPKAPK3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAPKAPK3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 382 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPKAP Kinase 3

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Andere Bezeichnung: MAPKAPK3 (MAPKAPK3 Produkte)

Synonyme: 3PK antikoerper, MAPKAP-K3 antikoerper, MAPKAP3 antikoerper, MAPKAPK-3 antikoerper, MK-3 antikoerper, AI874665 antikoerper, MK3 antikoerper, MapkKapk3 antikoerper, MAPKAPK3 antikoerper, mapkapk3 antikoerper, MGC154360 antikoerper, 3pk antikoerper, mapkap3 antikoerper, zgc:158342 antikoerper, mitogen-activated protein kinase-activated protein kinase 3 antikoerper, mitogen-activated protein kinase-activated protein kinase 3 S homeolog antikoerper, MAPKAPK3 antikoerper, Mapkapk3 antikoerper, mapkapk3.S antikoerper, mapkapk3 antikoerper

Hintergrund: MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
Alias Symbols: 3PK, MAPKAP3, MK-3, MAPKAP-K3, MAPKAPK-3
Protein Interaction Partner: UBC, TCF3, MAPK11, MAPK14, HSPB1, APP, LNX1, RNF2, PHC2, BMI1, Nedd4, NEDD4L, COPS6, SUMO3, SMS, RAB2A, IGHM, EZH2, MAPK13, EEF2K, EEF2, CBX4,
Protein Size: 382

Molekulargewicht: 43 kDa

Gen-ID: 7867

NCBI Accession: NM_004635, NP_004626

UniProt: Q16644

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades