CD55 Antikörper (Middle Region)

Produktnummer ABIN2788355

Der Kaninchen Polyklonal anti-CD55 Antikörper wird verwendet zum Nachweis von CD55 in Proben von Human, Hund und Pferd. Er wurde validiert für WB.

Kurzübersicht für CD55 Antikörper (Middle Region) (ABIN2788355)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reaktivität: Human, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD55 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD55 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: CD55 Antibody - middle region

Sequenz: PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI

Homologie: Dog: 79%, Horse: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CD55. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CD55

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60155-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: CD55

Hintergrund:

Background Information: This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.

Gene Name: CD55 Molecule, decay accelerating factor for complement (Cromer blood group)

Alternative Symbols: CR, TC, DAF, CROM, CHAPLE

Protein Name: Complement decay-accelerating factor

Molekulargewicht: 41kDa

Gen-ID: 1604

NCBI Accession: NP_000565

UniProt: P08174

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity