Adenosine A3 Receptor Antikörper (C-Term)

Produktnummer ABIN2788278

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-Adenosine A3 Receptor Antikörper (ABIN2788278) detektiert spezifisch Adenosine A3 Receptor in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Schwein, Rind (Kuh), Pferd und Kaninchen.

Kurzübersicht für Adenosine A3 Receptor Antikörper (C-Term) (ABIN2788278)

Target: Adenosine A3 Receptor (ADORA3)

Reaktivität: Human, Schwein, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenosine A3 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Adenosine A3 Receptor Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ADORA3 Antibody - C-terminal region

Sequenz: RSCKAPKVVR KADRSRTSIL IICILITGLG IISVISHLTK RRRSQRNRRV

Homologie: Cow: 75%, Horse: 93%, Human: 100%, Pig: 85%, Rabbit: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ADORA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59956-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Adenosine A3 Receptor Antikörper (ABIN2788278)

Merighi, Benini, Mirandola, Gessi, Varani, Leung, Maclennan, Baraldi, Borea: "Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells." in: Molecular pharmacology, Vol. 72, Issue 1, pp. 162-72, (2007) (PubMed).

Details zu Adenosine A3 Receptor

Target: Adenosine A3 Receptor (ADORA3)

Andere Bezeichnung: ADORA3

Hintergrund:

Background Information: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Adenosine A3 receptor

Alternative Symbols: A3AR

Protein Name: Protein ADORA3, isoform 3

Molekulargewicht: 30kDa

Gen-ID: 140

NCBI Accession: NP_001075445

UniProt: Q5QNY7

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process