DNAJC2 Antikörper (C-Term)

Produktnummer ABIN2788243

Der Kaninchen Polyklonal Anti-DNAJC2-Antikörper wurde für WB validiert. Er ist geeignet, DNAJC2 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd und Meerschweinchen zu detektieren.

Kurzübersicht für DNAJC2 Antikörper (C-Term) (ABIN2788243)

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DNAJC2 Antikörper

Bindungsspezifität: C-Term

Sequenz: EINEQIRKEK EEAEARMRQA SKNTEKSTGG GGNGSKNWSE DDLQLLIKAV

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DNAJC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DNAJC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 621 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DNAJC2

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Andere Bezeichnung: DNAJC2

Hintergrund: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
Alias Symbols: MPHOSPH11, MPP11, ZRF1, ZUO1
Protein Interaction Partner: HIST2H2AA3, UBC, RNF2, HSPA14, HSPA8,
Protein Size: 621

Molekulargewicht: 72 kDa

Gen-ID: 27000

NCBI Accession: NM_014377, NP_055192

UniProt: Q99543

Pathways: Chromatin Binding