BBS2 Antikörper (N-Term)

Produktnummer ABIN2788195

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BBS2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio) und Meerschweinchen.

Kurzübersicht für BBS2 Antikörper (N-Term) (ABIN2788195)

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BBS2 Antikörper

Bindungsspezifität: N-Term

Sequenz: GSDLFWTVTG DNVNSLALCD FDGDGKKELL VGSEDFDIRV FKEDEIVAEM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against BBS2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BBS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 721 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BBS2

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Andere Bezeichnung: BBS2

Hintergrund: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.
Alias Symbols: BBS, MGC20703
Protein Interaction Partner: PSME3, MDFI, RBPMS, GLIS2, HSCB, FHOD1, EXOC7, PAX2, KRT18, EPAS1, EEF1A1, BHMT, ALDOB, UBC, UBD,
Protein Size: 721

Molekulargewicht: 80 kDa

Gen-ID: 583

NCBI Accession: NM_031885, NP_114091

UniProt: Q9BXC9

Pathways: Hedgehog Signalweg