alpha 2 Macroglobulin Antikörper (N-Term)

Produktnummer ABIN2787981

Dieses Anti-alpha 2 Macroglobulin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von alpha 2 Macroglobulin in WB und IHC. Geeignet für Human.

Kurzübersicht für alpha 2 Macroglobulin Antikörper (N-Term) (ABIN2787981)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-alpha 2 Macroglobulin Antikörper

Bindungsspezifität: N-Term

Sequenz: PVPGHVTVSI CRKYSDASDC HGEDSQAFCE KFSGQLNSHG CFYQQVKTKV

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against A2M. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1474 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Andere Bezeichnung: A2M

Hintergrund: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD
Protein Interaction Partner: MAPK6, CDK7, CDK11A, HIPK1, FBXO6, CFTR, TP63, TGM2, IFIT3, DNAJB1, GCDH, FARSA, ENO2, ELAVL3, CYP2C18, CYP2C8, ATP1A1, APP, APOE, ACTB, A2M, RNF32, SWSAP1, TRAPPC5, EVI5L, EGLN2, IGSF8, PRAM1, MLST8, STAMBPL1, RETN, FBXL12, ECSIT, FIS1, EXOSC1, IFIT5, NC
Protein Size: 1474

Molekulargewicht: 161 kDa

Gen-ID: 2

NCBI Accession: NM_000014, NP_000005

UniProt: P01023

Pathways: Lipid Metabolism