LKB1 Antikörper (C-Term)

Produktnummer ABIN2787893

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LKB1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Pferd, Meerschweinchen und Rind (Kuh).

Kurzübersicht für LKB1 Antikörper (C-Term) (ABIN2787893)

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Pferd, Meerschweinchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LKB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-LKB1 Antikörper

Bindungsspezifität: C-Term

Sequenz: EAPVPIPPSP DTKDRWRSMT VVPYLEDLHG ADEDEDLFDI EDDIIYTQDF

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against STK11. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human STK11

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 433 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LKB1

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Andere Bezeichnung: STK11

Hintergrund: STK11is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in its gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Alias Symbols: LKB1, PJS, hLKB1
Protein Interaction Partner: SPDEF, SIRT1, PRKAA1, ETV4, CDC37, HSP90AA1, TP63, Eif2b1, Ap2m1, SNRK, APP, TNIP2, SIK1, STRADA, STUB1, UBE2D2, MARK2, GSK3B, STRADB, CAB39, KIF23, USP11, SMARCC1, SMARCA4, LIMS1, HSPA1A, FKBP5, RPAP3, MARK4, UBC, CAB39L, WDR48, RPS6KB1, MOB4, MARK1, RPS
Protein Size: 433

Molekulargewicht: 49 kDa

Gen-ID: 6794

NCBI Accession: NM_000455, NP_000446

UniProt: Q15831

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt