FN3KRP Antikörper (N-Term)

Produktnummer ABIN2787771

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-FN3KRP Antikörper (ABIN2787771) detektiert spezifisch FN3KRP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Hund, Meerschweinchen und Pferd.

Kurzübersicht für FN3KRP Antikörper (N-Term) (ABIN2787771)

Target: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FN3KRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FN3KRP Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FN3KRP Antibody - N-terminal region

Sequenz: MDPGDPAGDP AAGERHRMGR DPLLLLQALQ TLWSTRERKQ LREEAWRGFA

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FN3KRP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FN3KRP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58624-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FN3KRP Antikörper (ABIN2787771)

Szwergold, Manevich, Payne, Loomes: "Fructosamine-3-kinase-related-protein phosphorylates glucitolamines on the C-4 hydroxyl: novel substrate specificity of an enigmatic enzyme." in: Biochemical and biophysical research communications, Vol. 361, Issue 4, pp. 870-5, (2007) (PubMed).

Details zu FN3KRP

Target: FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))

Andere Bezeichnung: FN3KRP

Hintergrund:

Background Information: FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).[supplied by OMIM].

Gene Name: Fructosamine 3 kinase related protein

Alternative Symbols: FN3KL

Protein Name: Ketosamine-3-kinase

Molekulargewicht: 34kDa

Gen-ID: 79672

NCBI Accession: NP_078895

UniProt: Q9HA64