DDAH2 Antikörper (N-Term)

Produktnummer ABIN2787766

Dieser Anti-DDAH2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von DDAH2 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Pferd und Kaninchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für DDAH2 Antikörper (N-Term) (ABIN2787766)

Target: DDAH2 (Dimethylarginine Dimethylaminohydrolase 2 (DDAH2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDAH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DDAH2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MGTPGEGLGR CSHALIRGVP ESLASGEGAG AGLPALDLAK AQREHGVLGG

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DDAH2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDAH2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 285 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DDAH2 Antikörper (ABIN2787766)

Deer, Krames, Hassenbusch, Burton, Caraway, Dupen, Eisenach, Erdek, Grigsby, Kim, Levy, McDowell, Mekhail, Panchal, Prager, Rauck, Saulino, Sitzman, Staats, Stanton-Hicks, Stearns, Dean Willis, Witt, Follett, Huntoon, Liem, Rathmell, Wallace, Buchser, Cou: "Management of Intrathecal Catheter-Tip Inflammatory Masses: An Updated 2007 Consensus Statement From An Expert Panel." in: Neuromodulation : journal of the International Neuromodulation Society, Vol. 11, Issue 2, pp. 77-91, (2011) (PubMed).

Details zu DDAH2

Target: DDAH2 (Dimethylarginine Dimethylaminohydrolase 2 (DDAH2))

Andere Bezeichnung: DDAH2

Hintergrund: DDAH2 hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. DDAH2 has therefore a role in nitric oxide generation.This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DDAH, DDAHII, G6a, NG30
Protein Interaction Partner: VAC14, UBC, TRIP13, VCAM1, FN1, CDC73, TAF1D, ZAK, DNAJB11, GADD45G, RPS6KA5, TSC22D1, TNFSF11, MKNK1, TK1, STK3, SMN1, RPS6KA1, RAP1B, PIN1, RCC1, CDKN1A, CDK4, ATP1B1, ANXA7,
Protein Size: 285

Molekulargewicht: 31 kDa

Gen-ID: 23564

NCBI Accession: NM_013974, NP_039268

UniProt: O95865