EPH Receptor A5 Antikörper (Middle Region)

Produktnummer ABIN2787691

Produktdetails anti-EPH Receptor A5 Antikörper

Target: EPH Receptor A5 (EPHA5)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SDMGYVHRDL AARNILINSN LVCKVSDFGL SRVLEDDPEA AYTTRGGKIP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EPHA5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPHA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1037 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EPH Receptor A5 Antikörper (ABIN2787691)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Details zu EPH Receptor A5

Target: EPH Receptor A5 (EPHA5)

Andere Bezeichnung: EPHA5 (EPHA5 Produkte)

Synonyme: CEK7 antikoerper, EHK-1 antikoerper, EHK1 antikoerper, EK7 antikoerper, HEK7 antikoerper, TYRO4 antikoerper, AI854630 antikoerper, AW125296 antikoerper, Cek7 antikoerper, Ehk1 antikoerper, Els1 antikoerper, Hek7 antikoerper, Rek7 antikoerper, bsk antikoerper, Els1. antikoerper, EPHA5 antikoerper, EPH receptor A5 antikoerper, Eph receptor A5 antikoerper, EPHA5 antikoerper, epha5 antikoerper, Epha5 antikoerper

Hintergrund: EPHA5 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Two transcript variants encoding different isoforms have been found for this gene.This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Alias Symbols: CEK7, EHK1, HEK7, TYRO4
Protein Interaction Partner: NEDD4, UBC, EFNA2, EFNA5, EFNA3, EFNA4, EFNA1, STAT3,
Protein Size: 1037

Molekulargewicht: 114 kDa

Gen-ID: 2044

NCBI Accession: NM_004439, NP_004430

UniProt: P54756

Pathways: RTK Signalweg