EPH Receptor A5 Antikörper (AA 246-514)

Produktnummer ABIN7151843

Produktdetails anti-EPH Receptor A5 Antikörper

Target: EPH Receptor A5 (EPHA5)

Bindungsspezifität: AA 246-514

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ephrin type-A receptor 5 protein (246-514AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EPH Receptor A5

Target: EPH Receptor A5 (EPHA5)

Andere Bezeichnung: EPHA5 (EPHA5 Produkte)

Synonyme: CEK7 antikoerper, EHK-1 antikoerper, EHK1 antikoerper, EK7 antikoerper, HEK7 antikoerper, TYRO4 antikoerper, AI854630 antikoerper, AW125296 antikoerper, Cek7 antikoerper, Ehk1 antikoerper, Els1 antikoerper, Hek7 antikoerper, Rek7 antikoerper, bsk antikoerper, Els1. antikoerper, EPHA5 antikoerper, EPH receptor A5 antikoerper, Eph receptor A5 antikoerper, EPHA5 antikoerper, epha5 antikoerper, Epha5 antikoerper

Hintergrund:

Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).

Aliases: Brain-specific kinase antibody, bsk antibody, CEK 7 antibody, Eck like sequence 1 antibody, EHK 1 antibody, EHK-1 antibody, EK7 antibody, Els 1 antibody, EPH homology kinase 1 antibody, EPH-like kinase 7 antibody, EPHA5 antibody, EPHA5_HUMAN antibody, Ephrin type A receptor 5 antibody, Ephrin type-A receptor 5 antibody, HEK 7 antibody, hEK7 antibody, Receptor protein tyrosine kinase HEK 7 antibody, Rek 7 antibody, TYRO 4 antibody, Tyrosine protein kinase receptor EHK 1 antibody

UniProt: P54756

Pathways: RTK Signalweg