CARD9 Antikörper (Middle Region)

Produktnummer ABIN2787348

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CARD9 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Pferd und Hund.

Kurzübersicht für CARD9 Antikörper (Middle Region) (ABIN2787348)

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Reaktivität: Human, Maus, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CARD9 Antikörper

Bindungsspezifität: Middle Region

Sequenz: ALHQEQVLRN PHDAGLSSGE PPEKERRRLK ESFENYRRKR ALRKMQKGWR

Homologie: Dog: 92%, Horse: 86%, Human: 100%, Mouse: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against CARD9. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CARD9

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 536 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Andere Bezeichnung: CARD9

Hintergrund: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
Alias Symbols: hCARD9, CANDF2
Protein Interaction Partner: KRTAP10-3, MFAP1, MEOX2, LMO1, ABLIM1, KRT31, KRT19, PHC2, DAXX, TRIM23, AES, KRTAP10-5, KRTAP10-1, CCDC36, TRIM42, CEP57L1, RTP5, PPP1R18, TCEANC, ALS2CR11, ZNF417, CWF19L2, ZNF572, KRT40, SSX2IP, PNMA5, C1orf94, ZNF587, LZTS2, ZCCHC7, FAM161A, CEP70, FA
Protein Size: 536

Molekulargewicht: 62 kDa

Gen-ID: 64170

NCBI Accession: NM_052813, NP_434700

UniProt: Q9H257

Pathways: Activation of Innate immune Response