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TDP1 Antikörper (C-Term)

TDP1 Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2787113
  • Target Alle TDP1 Antikörper anzeigen
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 41
    • 14
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 34
    • 7
    • 1
    Kaninchen
    Klonalität
    • 37
    • 5
    Polyklonal
    Konjugat
    • 28
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Dieser TDP1 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GRPPGKSAVP LHLIYPSVEN VRTSLEGYPA GGSLPYSIQT AEKQRWLHSY
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against Tdp1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of mouse TDP1
    Top Product
    Discover our top product TDP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Andere Bezeichnung
    Tdp1 (TDP1 Produkte)
    Synonyme
    2810481F14Rik antikoerper, 4921509N21Rik antikoerper, AI838772 antikoerper, AW493413 antikoerper, E430034L06Rik antikoerper, MLZ-501 antikoerper, SCAN1 antikoerper, tdp1 antikoerper, MGC83708 antikoerper, TDP1 antikoerper, F8M21.60 antikoerper, F8M21_60 antikoerper, tyrosyl-DNA phosphodiesterase 1 antikoerper, tyrosyl-DNA phosphodiesterase 1 antikoerper, tyrosyl-DNA Phosphodiesterase (Tdp1) antikoerper, tyrosyl-DNA phosphodiesterase 1 L homeolog antikoerper, tyrosyl-DNA phosphodiesterase-like protein antikoerper, TDP1 antikoerper, Tc00.1047053511191.10 antikoerper, Tdp1 antikoerper, tdp1.L antikoerper, tdp1 antikoerper, PTRG_11198 antikoerper, MCYG_02121 antikoerper, MGYG_03035 antikoerper
    Hintergrund
    The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
    Protein Size: 609
    Molekulargewicht
    66 kDa
    Gen-ID
    55775
    NCBI Accession
    NM_001008744, NP_001008744
    UniProt
    Q9NUW8
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