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TDP1 Antikörper (C-Term)
TDP1
Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Zebrafisch (Danio rerio)
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2787113
Produktdetails anti-TDP1 Antikörper
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Target
Alle TDP1 Antikörper anzeigen
TDP1
(Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
Bindungsspezifität
Alle Epitope für TDP1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für TDP1 Antikörper
Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Zebrafisch (Danio rerio)
Wirt
Alle Wirte für TDP1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TDP1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für TDP1 Antikörper
Dieser TDP1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TDP1 Antikörper
Western Blotting (WB)
Sequenz
GRPPGKSAVP LHLIYPSVEN VRTSLEGYPA GGSLPYSIQT AEKQRWLHSY
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
Produktmerkmale
This is a rabbit polyclonal antibody against Tdp1. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of mouse TDP1
Top Product
Discover our top product TDP1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu TDP1
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Target
TDP1
(Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
Andere Bezeichnung
Tdp1 (TDP1 Produkte )
Synonyme
2810481F14Rik antikoerper, 4921509N21Rik antikoerper, AI838772 antikoerper, AW493413 antikoerper, E430034L06Rik antikoerper, MLZ-501 antikoerper, SCAN1 antikoerper, tdp1 antikoerper, MGC83708 antikoerper, TDP1 antikoerper, F8M21.60 antikoerper, F8M21_60 antikoerper, tyrosyl-DNA phosphodiesterase 1 antikoerper, tyrosyl-DNA phosphodiesterase 1 antikoerper, tyrosyl-DNA Phosphodiesterase (Tdp1) antikoerper, tyrosyl-DNA phosphodiesterase 1 L homeolog antikoerper, tyrosyl-DNA phosphodiesterase-like protein antikoerper, TDP1 antikoerper, Tc00.1047053511191.10 antikoerper, Tdp1 antikoerper, tdp1.L antikoerper, tdp1 antikoerper, PTRG_11198 antikoerper, MCYG_02121 antikoerper, MGYG_03035 antikoerper
Hintergrund
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. Protein Size: 609
Molekulargewicht
66 kDa
Gen-ID
55775
NCBI Accession
NM_001008744 , NP_001008744
UniProt
Q9NUW8
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