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TDP1 Antikörper (AA 1-140)

TDP1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1682992
  • Target Alle TDP1 Antikörper anzeigen
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-140
    Reaktivität
    • 41
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 34
    • 7
    • 1
    Kaninchen
    Klonalität
    • 37
    • 5
    Polyklonal
    Konjugat
    • 28
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Dieser TDP1 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE
    Kreuzreaktivität
    Human, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TDP1 (NP_060789.2).
    Isotyp
    IgG
    Top Product
    Discover our top product TDP1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Andere Bezeichnung
    TDP1 (TDP1 Produkte)
    Hintergrund
    The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).,TDP1,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,TDP1
    Molekulargewicht
    41 kDa/68 kDa
    Gen-ID
    55775
    UniProt
    Q9NUW8
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