PRR5 Antikörper (N-Term)

Produktnummer ABIN2786881

Produktdetails anti-PRR5 Antikörper

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NSIHNGVIAV FQRKGLPDQE LFSLNEGVRQ LLKTELGSFF TEYLQNQLLT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRR5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRR5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 379 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRR5

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Andere Bezeichnung: PRR5 (PRR5 Produkte)

Synonyme: AU043908 antikoerper, Arhgap8 antikoerper, C030017C09Rik antikoerper, C78947 antikoerper, Protor-1 antikoerper, Protor1 antikoerper, FLJ20185k antikoerper, PP610 antikoerper, PROTOR-1 antikoerper, PROTOR1 antikoerper, pp610 antikoerper, protor1 antikoerper, protor2 antikoerper, proline rich 5 (renal) antikoerper, proline rich 5 antikoerper, proline rich 5 L homeolog antikoerper, Prr5 antikoerper, PRR5 antikoerper, prr5.L antikoerper

Hintergrund: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. Rare read-through transcripts, containing exons from the ARHGAP8 gene which is located immediately downstream, led to the original description of PRR5 and ARHGAP8 as a single gene. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms.
Alias Symbols: FLJ20185, FLJ20185k, PP610, PROTOR1, PROTOR-1
Protein Interaction Partner: MTOR, BRCA1, UBC, RICTOR, MAPKAP1, MLST8,
Protein Size: 379

Molekulargewicht: 41 kDa

Gen-ID: 55615

NCBI Accession: NM_015366, NP_056181

UniProt: B3KRM4

Pathways: PI3K-Akt Signalweg