PKC delta Antikörper (N-Term)

Produktnummer ABIN2786851

Der Kaninchen Polyklonal Anti-PKC delta-Antikörper wurde für WB validiert. Er ist geeignet, PKC delta in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd und Meerschweinchen zu detektieren.

Kurzübersicht für PKC delta Antikörper (N-Term) (ABIN2786851)

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC delta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PKC delta Antikörper

Bindungsspezifität: N-Term

Sequenz: NSYELGSLQV EDEASQPFCA VKMKEALSTE RGKTLVQKKP TMYPEWKTTF

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Prkcd. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of mouse PRKCD

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PKC delta

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Andere Bezeichnung: Prkcd

Hintergrund: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.
Alias Symbols: MAY1, PKCD, ALPS3, CVID9, nPKC-delta
Protein Size: 487

Molekulargewicht: 53 kDa

Gen-ID: 5580

NCBI Accession: NM_001316327, NP_001303256

UniProt: Q05655

Pathways: Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism