Mre11 Antikörper (Middle Region)
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- Target Alle Mre11 (MRE11A) Antikörper anzeigen
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Hund, Kaninchen, Meerschweinchen, Rind (Kuh), Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Mre11 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RFRETRQKNT NEEDDEVREA MTRARALRSQ SEESASAFSA DDLMSIDLAE
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MRE11A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MRE11A
- Top Product
- Discover our top product MRE11A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 708 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Andere Bezeichnung
- MRE11A (MRE11A Produkte)
- Synonyme
- wu:faa63d12 antikoerper, zgc:64018 antikoerper, Mre11 antikoerper, Mre11b antikoerper, ATLD antikoerper, HNGS1 antikoerper, MRE11 antikoerper, MRE11B antikoerper, MRE11 homolog A, double strand break repair nuclease antikoerper, MRE11 homolog, double strand break repair nuclease antikoerper, MRE11A homolog A, double strand break repair nuclease antikoerper, mre11a antikoerper, MRE11 antikoerper, Mre11a antikoerper
- Hintergrund
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This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: ATLD, HNGS1, MRE11, MRE11B
Protein Interaction Partner: HUWE1, CIAO1, ATRX, BRCA1, RPA3, RPA2, RPA1, EED, ABCF1, C14orf166, RTCB, RPL26L1, NELFB, IGF2BP3, LRRFIP1, MAP7, EIF2B2, EIF2B3, YBX3, RPL27, RFC4, QARS, NMT1, HNRNPM, ILF2, HNRNPU, HNRNPA2B1, FLII, DHX9, DDX1, LMNA, PAN2, UBC, MCM2, GINS1, MDC1, RNF8, C
Protein Size: 708 - Molekulargewicht
- 80 kDa
- Gen-ID
- 4361
- NCBI Accession
- NM_005591, NP_005582
- UniProt
- P49959
- Pathways
- DNA Reparatur
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