RANGAP1 Antikörper (N-Term)

Produktnummer ABIN2786743

Dieses Anti-RANGAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RANGAP1 in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für RANGAP1 Antikörper (N-Term) (ABIN2786743)

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RANGAP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MASEDIAKLA ETLAKTQVAG GQLSFKGKSL KLNTAEDAKD VIKEIEDFDS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RANGAP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RANGAP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 587 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RANGAP1 Antikörper (ABIN2786743)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu RANGAP1

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Andere Bezeichnung: RANGAP1

Hintergrund: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA
Alias Symbols: Fug1, KIAA1835, MGC20266, SD
Protein Interaction Partner: SENP2, SENP1, SUMO1, UBE2I, SUMO2, SUMO3, RANBP2, UBC, NEDD8, RNF2, rev, TP53RK, EFTUD1, NIF3L1, RPRD1B, OSGEP, PANK4, THG1L, NSUN2, UFM1, IPO11, SH3GLB1, TPRKB, EEF2K, DBNL, KIAA1279, ACTR2, ACTR3, ARPC1B, SAE1, TPD52L2, PPP2R5D, LPP, CALU, BAG1, ARPC2,
Protein Size: 587

Molekulargewicht: 63 kDa

Gen-ID: 5905

NCBI Accession: NM_002883, NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus