MAPK13 Antikörper (Middle Region)

Produktnummer ABIN2786702

Produktdetails anti-MAPK13 Antikörper

Target: MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Ziege, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd, Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EMLTGKTLFK GKDYLDQLTQ ILKVTGVPGT EFVQKLNDKA AKSYIQSLPQ

Homologie: Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 77%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 85%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MAPK13. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAPK13

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 365 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPK13

Target: MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))

Andere Bezeichnung: MAPK13 (MAPK13 Produkte)

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Alias Symbols: MGC99536, PRKM13, SAPK4, p38delta
Protein Interaction Partner: MAPK13, MAPT, SMAD4, GPX4, VCP, APP, HTRA2, MBP, UBC, AKIP1, ANKLE2, MAPKAPK5, EEF2K, MAP3K4, MAPKAPK3, MAP2K6, ATF2, MAPK8IP2, FGF12,
Protein Size: 365

Molekulargewicht: 42 kDa

Gen-ID: 5603

NCBI Accession: NM_002754, NP_002745

UniProt: Q9N272

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Hepatitis C, BCR Signaling, S100 Proteine