MAP3K11 Antikörper (Middle Region)
Kurzübersicht für MAP3K11 Antikörper (Middle Region) (ABIN2786655)
Target
Alle MAP3K11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- PVGQRSAKSP RREEEPRGGT VSPPPGTSRS APGTPGTPRS PPLGLISRPR
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Homologie
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MAP3K11. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MAP3K11
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 847 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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Andere Bezeichnung
- MAP3K11
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Hintergrund
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The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK sig
Alias Symbols: MGC17114, MLK-3, MLK3, PTK1, SPRK, MEKK11
Protein Interaction Partner: STUB1, UBC, HSP90AA1, HSPA4, APP, CDC37, MAP2K7, HSP90AB1, PIN1, GSK3B, GSK3A, EPS8, MAPK8IP1, TRAF6, MAP3K11, CBL, MAP4K2, TRIM5, CLEC4G, TRAF2, COPS5, SH3RF1, MAPK8IP3, MAPK8IP2, KIF3A, IKBKB, RAC1, MAP4K1, CHUK, MAP3K12, RHOG, AKT1, CDC42, MAP2K4, DLG4
Protein Size: 847 -
Molekulargewicht
- 93 kDa
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Gen-ID
- 4296
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NCBI Accession
- NM_002419, NP_002410
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UniProt
- Q16584
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Pathways
- MAPK Signalweg, Interferon-gamma Pathway
Target
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