ACO2 Antikörper (C-Term)

Produktnummer ABIN2786628

Der Kaninchen Polyklonal Anti-ACO2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ACO2 in Proben von Human, Ratte, Schwein, Rind (Kuh) und Saccharomyces cerevisiae zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für ACO2 Antikörper (C-Term) (ABIN2786628)

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reaktivität: Human, Ratte, Schwein, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ACO2 Antikörper

Bindungsspezifität: C-Term

Sequenz: RYYKKHGIRW VVIGDENYGE GSSREHAALE PRHLGGRAII TKSFARIHET

Homologie: Cow: 100%, Human: 100%, Pig: 100%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ACO2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ACO2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 780 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACO2 Antikörper (ABIN2786628)

Scheving, Wittig, Heide, Albuquerque, Steger, Brandt, Tegeder: "Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve." in: Journal of proteomics, Vol. 75, Issue 13, pp. 3987-4004, (2012) (PubMed).

Details zu ACO2

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Andere Bezeichnung: ACO2

Hintergrund: ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
Alias Symbols: ACONM, MGC20605, MGC33908
Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, MDM2, ASB9, VCAM1, ITGA4, AK3, SIN3A, ACAA2, APP, ACAT1, ATXN1L, SUMO4, PSMD4, SRRM2,
Protein Size: 780

Molekulargewicht: 82 kDa

Gen-ID: 50

NCBI Accession: NM_001098, NP_001089

UniProt: Q99798