K-RAS Antikörper (N-Term)

Produktnummer ABIN2786191

Der Kaninchen Polyklonal anti-K-RAS Antikörper wird verwendet zum Nachweis von K-RAS in Proben von Human, Ratte, Maus, Hund, Zebrafisch (Danio rerio), Kaninchen, Pferd, Meerschweinchen, Rind (Kuh) und Saccharomyces cerevisiae. Er wurde validiert für WB.

Kurzübersicht für K-RAS Antikörper (N-Term) (ABIN2786191)

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Reaktivität: Human, Ratte, Maus, Hund, Zebrafisch (Danio rerio), Kaninchen, Pferd, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser K-RAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-K-RAS Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: KRAS Antibody - N-terminal region

Sequenz: TEYKLVVVGA GGVGKSALTI QLIQNHFVDE YDPTIEDSYR KQVVIDGETC

Spezifität: 100 % homologous to human KRAS, NRAS and HRAS.

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KRAS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KRAS

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55408-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Andere Bezeichnung: KRAS

Hintergrund:

Background Information: KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.

Gene Name: V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Alternative Symbols: NS, NS3, OES, CFC2, RALD, K-Ras, KRAS1, KRAS2, RASK2, KI-RAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras 2, C-K-RAS, c-Ki-ras, c-Ki-ras2

Protein Name: GTPase NRas

Molekulargewicht: 22 kDa

Gen-ID: 3845

NCBI Accession: NP_203524

UniProt: P01111