POLM Antikörper (Middle Region)

Produktnummer ABIN2785958

Produktdetails anti-POLM Antikörper

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Schwein, Kaninchen, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRRFSRKEKG LWLNSHGLFD PEQKTFFQAA SEEDIFRHLG LEYLPPEQRN

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against POLM. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POLM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 494 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu POLM

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Andere Bezeichnung: POLM (POLM Produkte)

Synonyme: polmu antikoerper, zgc:56122 antikoerper, POLM antikoerper, Pol Mu antikoerper, Tdt-N antikoerper, AI462166 antikoerper, B230309I03Rik antikoerper, polymerase (DNA directed), mu antikoerper, DNA polymerase mu antikoerper, polm antikoerper, POLM antikoerper, CC1G_09351 antikoerper, VDBG_09335 antikoerper, Polm antikoerper

Hintergrund: POLM seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.
Alias Symbols: Tdt-N, Pol Mu
Protein Interaction Partner: CEP55, IKZF3, PNMA1, PCNA, UBE2C, UBE2H, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
Protein Size: 494

Molekulargewicht: 55 kDa

Gen-ID: 27434

NCBI Accession: NM_013284, NP_037416

UniProt: Q9NP87

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response