POLM Antikörper (AA 210-290)

Produktnummer ABIN7217760

Der Kaninchen Polyklonal anti-POLM Antikörper (ABIN7217760) detektiert spezifisch POLM in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für POLM Antikörper (AA 210-290) (ABIN7217760)

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-POLM Antikörper

Bindungsspezifität: AA 210-290

Verwendungszweck: Rabbit Anti-DNA Pol μ Polyclonal Antibody

Spezifität: DNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human DNA Pol mu at AA range: 210-290

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu POLM

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Andere Bezeichnung: DNA Pol mu

Hintergrund: POLM, polmu, DNA-directed DNA/RNA polymerase mu, Pol Mu, Terminal transferasePOLM (Polymerase (DNA) Mu) is a Protein Coding gene. Among its related pathways are Platinum Pathway, Pharmacokinetics/Pharmacodynamics and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include DNA-directed DNA polymerase activity and DNA polymerase activity. An important paralog of this gene is POLB. Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.

Molekulargewicht: 54kD

Gen-ID: 27434

UniProt: Q9NP87

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response