Galectin 3 Antikörper (N-Term)

Produktnummer ABIN2785832

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Galectin 3 Antikörper wird verwendet zum Nachweis von Galectin 3 in Proben von Human, Maus, Ratte, Kaninchen, Schwein, Rind (Kuh), Hund, Meerschweinchen und Pferd. Er wurde validiert für WB und IHC.

Kurzübersicht für Galectin 3 Antikörper (N-Term) (ABIN2785832)

Target: Galectin 3 (LGALS3)

Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Galectin 3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LGALS3 Antibody - N-terminal region

Sequenz: GASYPGAYPG QAPPGAYPGQ APPGAYPGAP GAYPGAPAPG VYPGPPSGPG

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against LGALS3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54688-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Galectin 3 Antikörper (ABIN2785832)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: LGALS3

Hintergrund:

Background Information: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Gene Name: galectin 3

Alternative Symbols: L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2

Protein Name: galectin-3

Molekulargewicht: 26kDa

Gen-ID: 3958

NCBI Accession: NP_002297

UniProt: P17931

Pathways: RTK Signalweg